Poly(lactic acid)/poly(lactic-co-glycolic acid) particulate carriers for pulmonary drug delivery
نویسندگان
چکیده
منابع مشابه
Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid
BACKGROUND Nanoparticles fabricated from the biodegradable and biocompatible polymer, polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug delivery systems. The objective of this study was to explore fully the development of a PLGA nanoparticle drug delivery system for alternative preparation of a commercial formulation. In our nanoparticle fabrication, ou...
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Poly(D,L-lactide-co-glycolide) (PLGA) is the most frequently used biodegradable polymer for developing nano/ microparticles encapsulating therapeutic drugs in controlled release (CR) applications. PLGA based drug delivery devices have several advantages over the conventional devices. One of the advantage is the extended release rates of drugs up to days, weeks or months. Other reasons for the w...
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Purpose Poly(lactic-co-glycolic acid) (PLGA) is widely used for drug delivery because of its biocompatibility, ability to solubilize a wide variety of drugs, and tunable degradation. However, achieving sub-100 nm nanoparticles (NPs), as might be desired for delivery via the enhanced permeability and retention effect, is extremely difficult via typical top-down emulsion approaches. Methods Her...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Investigation
سال: 2019
ISSN: 2093-5552,2093-6214
DOI: 10.1007/s40005-019-00443-1